Join a dynamic team where everyone contributes their ideas and talents towards a variety of diverse projects. We are a state-of-the-art laboratory with flexible work hours.
We are seeking a professional-level organic chemist to join our drug discovery team. You'll contribute to hit-to-lead development, lead optimization, and synthetic route development. The ideal candidate will have hands-on synthetic chemistry experience, strong lab skills, and excel in collaborative problem-solving.
RESPONSIBILITIES:
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Utilize cutting-edge synthetic methodologies and techniques to design and execute efficient syntheses of target compounds for existing chemical series and novel series;
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Independently conduct multi-step synthesis and optimization through effective reaction planning, troubleshooting, and systematic analysis;
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Purify and characterize compounds using a variety of techniques including column chromatography, crystallization, trituration, LCMS, NMR, HPLC;
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Work under the supervision of the Director of Chemistry or the Project Manager in order to achieve the objectives of the project in line with those of the client;
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Research current literature to formulate synthetic and medicinal chemistry strategies. Evaluate and implement new reactions, techniques and technologies to advance the projects;
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Maintain lab notebook, instrument and inventory records in accord with department guidance;
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Maintain all appropriate standards for lab safety and hazardous material management.
REQUIREMENTS:
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MSc (10 years of experience) or PhD (5 years of experience) in Organic or Medicinal Chemistry;
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Project management experience;
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Strong knowledge of and experience in current synthetic methods;
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Expertise in isolation and purification techniques such as silica gel chromatography and HPLC as well as modern analytical techniques such as NMR and LCMS;
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Knowledge of good laboratory and safety practices.
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Excellent written, organizational and documentation skills;
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Proactive with strong interpersonal skills; able to thrive in a team-based environment;
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Demonstrated ability to troubleshoot and creatively problem solve;
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Proficiency in Microsoft Office (Word, Excel and PowerPoint);
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Ability to communicate progress effectively with colleagues and managers;
